Grainyhead, a master regulator that controls DNA access

A team led by Prof. Stein Aerts (VIB-KU Leuven) has reported how access to relevant DNA regions is orchestrated in epithelial cells. These findings shed new light on the biological mechanisms of gene regulation and open up ...

Researchers identify how eye loss occurs in blind cavefish

Loss of eye tissue in blind cavefish (Astyanax mexicanus), which occurs within a few days of their development, happens through epigenetic silencing of eye-related genes, according to a study led by the National Institutes ...

Three genes essential for cells to tell time

One family of genes allows cells to adapt to daily changes in environmental conditions by adjusting the circadian clock responsible for regular sleep-wake cycles. The new discovery by University of Tokyo scientists reveals ...

Scientists reveal how epigenetic changes in DNA are interpreted

A new study in Science from Karolinska Institutet maps out how different DNA-binding proteins in human cells react to certain biochemical modifications of the DNA molecule. The scientists report that some 'master' regulatory ...

Bacterial supermachine reveals streamlined protein assembly line

There are many processes that take place in cells that are essential for life. Two of these, transcription and translation, allow the genetic information stored in DNA to be deciphered into the proteins that form all living ...

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