New tool probes gene regulation

DNA methylation (DNAme) is a modification of the genome—an epigenetic "mark"—that is required for proper cellular differentiation. It has been implicated in the regulation of gene expression, but its role in this stepwise ...

Putting a finger on plant stress response

Post-translational modification is the process whereby proteins are modified after their initial biosynthesis. Modification can take many forms, including enzymatic cleavage of the protein or the addition of sugars, lipids, ...

New roles for DNA-packaging proteins

How can human cells pack 3-meter-long DNA into their tiny nuclei and unpack it only where and when it is needed? This fascinating process is far from being completely understood.

Finally, machine learning interprets gene regulation clearly

In this age of "big data," artificial intelligence (AI) has become a valuable ally for scientists. Machine learning algorithms, for instance, are helping biologists make sense of the dizzying number of molecular signals that ...

Gene expression regulation in Chinese cabbage illuminated

Doctoral student Ayasha Akter (Kobe University's Graduate School of Agricultural Science) and technical staff member Satoshi Takahashi (from the RIKEN Center for Sustainable Resource Science) have revealed the important role ...

Scientists detail how chromosomes reorganize after cell division

Researchers have discovered key mechanisms and structural details of a fundamental biological process—how a cell nucleus and its chromosomal material reorganizes itself after cell division. The new findings in chromosomal ...

Coordinating the removal of RNA-DNA hybrids

Two research teams led by Professors Brian Luke and Helle Ulrich at the Institute of Molecular Biology have deciphered how two enzymes, RNase H2 and RNase H1, are coordinated to remove RNA-DNA hybrid structures from chromosomes. ...

Self-restrained genes enable evolutionary novelty

Changes in the genes that control development can potentially make large contributions to evolution by generating new morphologies in plants and animals. However, because developmental genes frequently influence many different ...

MicroRNA comprehensively analyzed

Messenger RNA transmits genetic information to the proteins, and microRNA plays a key role in the regulation of gene expression. Scientists from the Moscow Institute of Physics and Technology and the Research Centre for Medical ...

page 13 from 29