Unravelling the function of small RNAs

Small non-coding RNAs (ncRNAs) play a hitherto unrecognised role in regulation of gene expression. To broaden knowledge on the function and evolution of these molecules, a EU project investigated various classes of regulatory ...

Conserved gene expression reveals our 'inner fish'

A study of gene expression in chickens, frogs, pufferfish, mice and people has revealed surprising similarities in several key tissues. Researchers writing in BioMed Central's open access Journal of Biology have shown that ...

Desert algae shed light on desiccation tolerance in green plants

Deserts of the U.S. Southwest are extreme habitats for most plants, but, remarkably, microscopic green algae live there that are extraordinarily tolerant of dehydration. These tiny green algae (many just a few microns in ...

Transcriptional elongation control takes on new dimensions

Life is complicated enough, so you can forgive the pioneers of DNA biology for glossing over transcriptional elongation control by RNA polymerase II, the quick and seemingly bulletproof penultimate step in the process that ...

Orchestrating development in the fly embryo

Most multicellular organisms on Earth—including you—begin as a single fertilized egg and then undergo a complex choreography of cellular growth to become a functioning adult composed of countless cells. Understanding ...

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