A large-scale study conducted by molecular biologists from Heidelberg University has yielded groundbreaking new insights into the evolution and regulation of gene expression in mammalian organs. The scientists investigated ...
Evolution
Nov 11, 2020
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(Phys.org)—Scientists from the Friedrich Miescher Institute for Biomedical Research and the Biozentrum of the University of Basel have published an important proof-of-principle study showing that a computational model can ...
Biotechnology
Dec 4, 2012
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Pioneering new research from a team of Indiana University Bloomington biologists has shown for the first time that a protein which has been long known to be critical for the initiation of protein synthesis in all organisms ...
Cell & Microbiology
Sep 18, 2013
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In a recent article published in Molecular Cell, Ali Shilatifard, Ph.D., the Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, and Yuki Aoi Ph.D., a postdoctoral fellow in Shilatifard laboratory, ...
Cell & Microbiology
Nov 3, 2023
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Berkeley Lab and UC Berkeley researchers have discovered that the transcription factor protein TFIID coexists in two distinct structural states, a key to genetic expression and TFIID's ability to initiate the process by which ...
Cell & Microbiology
Jan 17, 2013
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In multicellular organisms, all cells of an individual normally contain the same genetic information and cell differentiation is achieved through regulation of gene expression. There are exceptions, however, where, instead ...
Evolution
Aug 9, 2023
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Transcription activator-like effector (TALE) proteins can be designed to bind to almost any selected DNA. Researchers now report that a TALE can displace another TALE protein from DNA in a highly polarized way – it can ...
Cell & Microbiology
Nov 26, 2018
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How is the activity of genes regulated by the packaging of DNA? To answer this question, a technique to measure both gene expression and DNA packaging at the same time was developed by Franka Rang and Kim de Luca, researchers ...
Cell & Microbiology
Apr 1, 2022
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134
Regulation of gene expression—turning genes on or off, increasing or decreasing their expression—is critical for defining cell identity during development and coordinating cellular activity throughout the cell's lifetime. ...
Cell & Microbiology
Nov 19, 2018
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Whitehead Institute researchers have determined that DNA transcription, the process that produces messenger RNA (mRNA) templates used in protein production, also runs in the opposite direction along the DNA to create corresponding ...
Cell & Microbiology
Feb 4, 2013
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