Molecular sensor scouts DNA damage and supervises repair

In the time it takes you to read this sentence, every cell in your body suffers some form of DNA damage. Without vigilant repair, cancer would run rampant, and now scientists at the University of Pittsburgh have gotten a ...

Novel mechanism of inheritance detected

Non-Mendelian, oligogenic inheritance could be an unrecognized and important element for occurrence of hereditary retinal degenerations (HRDs, comprising retinitis pigmentosa) which are caused by ultra-rare mutations and ...

Sex and diet affect protein machineries

Scientists from EMBL Heidelberg have discovered that the collection of proteins in an animal cell—called the proteome—is substantially affected by both the animal's sex and its diet. Understanding these individual proteomes ...

A banner year for pharma

As 2018 draws to a close, the pharmaceutical industry is celebrating a prosperous year of new investments and therapeutic breakthroughs. These successes were driven by cutting-edge science and progress in finally translating ...

The function of many proteins remains unclear

The DNA of every organism holds the blueprints for building all the proteins it needs for its metabolic processes. While researchers already know what the blueprints look like for most proteins, they do not know what many ...

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