Solving the mystery behind how nutrients enter cells

For the nutrients that feed our cells to reach their destination, proteins embedded in the cell membrane often must shuttle what's needed across the threshold. When this system breaks down and metabolites fail to reach their ...

Structure of amyloid protein offers clues to rare disease cause

Researchers at the UAB have determined the structure of amyloid fibers formed by the protein hnRNPDL-2, implicated in limb-girdle muscular dystrophy type 3, using high-resolution cryo-electron microscopy (cryo-EM). They have ...

Novel mechanisms regulate inflammatory skin diseases

Investigators have identified a novel role for an intracellular trafficking pathway in regulating epidermal developmental processes, which could serve as a future therapeutic target for inflammatory skin diseases, according ...

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