Targeted small molecule alleviates arthritis symptoms in mice

Researchers at the University of Helsinki, together with researchers from the United States, have discovered a small molecule that inhibits the formation in cells of cytokine proteins that promote inflammation. The mechanism ...

Researchers present RNA-based nanodrug treatment for ovarian cancer

Ovarian cancer ranks fifth in cancer deaths among women, accounting for more deaths than any other cancer of the female reproductive system. In a study conducted at Tel Aviv University, researchers used protein CKAP5 (cytoskeleton-associated ...

Degrading viral RNA to treat SARS-CoV-2 infection

Development of vaccines against SARS-CoV-2 has been rapid, but the rise of variants forces scientists to frequently modify treatments. Ideally, therapies would target mutation-resistant viral proteins, but this has proven ...

A new way to study molecular drivers of cancer

A clearer understanding about the markers and drivers of cancer cell proliferation has emerged from research that identifies new opportunities to overcome convergence with complex enzymes, known as kinases. The work paves ...

A new control switch could make RNA therapies easier to program

Using an RNA sensor, MIT engineers have designed a new way to trigger cells to turn on a synthetic gene. Their approach could make it possible to create targeted therapies for cancer and other diseases, by ensuring that synthetic ...

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