A new method of identifying molecular targets to fight disease could help accelerate future drug development new Griffith University research published in Scientific Reports has found.
Cell & Microbiology
Jan 27, 2021
0
17
Scientists from Skoltech, the Institute of Bioorganic Chemistry of RAS and the London Institute of Medical Sciences (LMS) have developed an enhanced version of SuperNova, a genetically encoded phototoxic synthesizer, that ...
Biotechnology
Dec 17, 2020
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5
Imagine trying to throw a bullseye when the dartboard lies buried within a crumpled box. That's the challenge faced by scientists working to make new medicines for some 'undruggable' diseases, including a type of metastatic ...
Biochemistry
Dec 15, 2020
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49
Some useful drugs consist of peptides acting on their protein targets. To make them more efficient and stable, scientists have found a way to replace crucial segments of the peptides with ureido units. These oligoureas, which ...
Biochemistry
Dec 7, 2020
1
9
Researchers can now more accurately and precisely target specific proteins in yeast, mammalian cells and mice to study how knocking down specific protein traits can influence physical manifestation in a cell or organism.
Molecular & Computational biology
Nov 11, 2020
0
214
A research team led by Nagoya University scientists in Japan has developed an approach that can quickly find synthetic proteins that specifically bind to important targets, such as components of the SARS-CoV-2 virus. The ...
Biochemistry
Oct 7, 2020
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40
Proteins transduce information and signals within the human body by changes in their structures. For example, hormones binding to their target proteins cause a structural change which in turn opens new binding sites for other ...
Molecular & Computational biology
Oct 6, 2020
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4
Researchers from Bochum, Düsseldorf and Dortmund have gained new insights into how the Stripak signal-protein complex works. They studied the complex, which occurs in all organisms with a cell nucleus, in the fungus Sordaria ...
Cell & Microbiology
Oct 6, 2020
0
5
An innovative genetic study of blood protein levels, led by researchers in the MRC Integrative Epidemiology Unit (MRC-IEU) at the University of Bristol, has demonstrated how genetic data can be used to support drug target ...
Biotechnology
Sep 7, 2020
0
56
A team of scientists at the Nagoya University Institute of Transformative Bio-Molecules (WPI-ITbM) have developed a method for visualizing microtubule dynamics and cell membrane protein endocytosis in living plant cells, ...
Plants & Animals
Aug 21, 2020
0
58
