Proteins are the "workhorses" in every living cell and constitute the chemical basis of life. These little machines are required to turn food into energy, to manage motion and brain activities and to fight off bacteria and ...
Molecular & Computational biology
Feb 16, 2022
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6
A structural analysis by an all-RIKEN team offers detailed insights into how the function of dedicator of cytokinesis (DOCK) proteins is modulated, and how known disease-related mutations derail that activity.
Cell & Microbiology
Nov 1, 2021
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29
Although profoundly different in terms of physiology, habitat and nutritional needs, plants and animals are confronted with one shared existential problem: how to keep themselves safe in the face of constant exposure to harmful ...
Cell & Microbiology
Nov 2, 2020
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21
Researchers at the University of São Paulo (USP) in Brazil have characterized a novel family of anti-bacterial toxins present in bacteria, including Salmonella enterica. This species uses toxic proteins to kill other bacteria ...
Cell & Microbiology
Sep 21, 2020
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15
Biophysicists from the MIPT Center for Molecular Mechanisms of Aging and Age-Related Diseases have teamed up with colleagues from Canada, the U.S., Japan, France, and Germany to shed light on the structure and functioning ...
Biotechnology
Jan 20, 2020
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56
In basic biology, medical sciences and pharmaceutical sciences, structural analyses of membrane proteins are important, and single-particle analysis by cryoEM is now very powerful method. Japanese researchers have developed ...
Biotechnology
Oct 3, 2019
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14
Protein nanomachines made of multiple protein molecules are highly dynamic during their actions on their functional targets, sometime called substrates. Dynamics of these large protein nanomachines of more than megadalton ...
Biochemistry
Feb 26, 2019
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7
Researchers from Charité - Universitätsmedizin Berlin have demonstrated on a molecular level how a specific protein allows light signals to be converted into cellular information. Their findings have broadened the understanding ...
Cell & Microbiology
Dec 4, 2018
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62
Some problems are so challenging to solve that even the most advanced computers need weeks, not seconds, to process them.
Computer Sciences
Jun 9, 2017
1
697
Membrane proteins make up approximately a quarter of all gene products and are the targets of over 50 percent of all modern pharmaceutical drugs. The inner mitochondrial membrane (IMM) proteome plays a central role in maintaining ...
Biochemistry
Apr 26, 2017
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