The protein problem

The importance of proteins is difficult to overstate; they play a critical role in countless biological processes. An enhanced understanding of their structure and function is essential to advancing the state of the art in ...

Shortcut to protein portraits

All living organisms, from bacteria to humans, rely on proteins to perform their vital functions. How these proteins accomplish their tasks depends on their structure. Researchers from the Paul Scherrer Institute have now ...

Scientists discover bacteria's clever defence mechanism

Scientists have uncovered important new information about how bacteria grow and multiply, potentially leading to the discovery of much-needed new antibiotic drugs. Using Diamond Light Source – the UK's synchrotron science ...

Crystallography scientists celebrate 500 protein structures

The Canadian Macromolecular Crystallography Facility (CMCF) has announced the successful solution of 500 protein structures using the Canadian Light Source. The 3-D structures of proteins can be determined using powerful ...

Scientists reveal details of calcium 'safety-valve' in cells

(Phys.org) —Sometimes a cell has to die—when it's done with its job or inflicted with injury that could otherwise harm an organism. Conversely, cells that refuse to die when expected can lead to cancer. So scientists ...

Doing more with less; in cellulo structure determinations

Anyone involved in macromolecular crystallography will know that for many years scientists have had to rely on a multi-stage process utilizing protein, usually expressed in engineered cells, which is then extracted and purified ...

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