Antibiotic medicines became a popular treatment for bacterial infections in the early 20th century and emerged as a transformational tool in human health. Through the middle of the century, novel antibiotics were regularly ...
Cell & Microbiology
May 1, 2024
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38
Scientists at the United States Department of Agriculture (USDA)'s Agricultural Research Service (ARS) have developed a green antibiotic alternative to treat the deadly pathogen Streptococcus iniae in hybrid striped bass, ...
Plants & Animals
Jan 30, 2024
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1
Protein degraders, a novel approach in drug discovery, show promise in tackling diseases previously thought to be untreatable. Unlike traditional drugs that block specific protein functions, degraders alter the cell's natural ...
Biochemistry
Jan 30, 2024
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8
Norwegian University of Science and Technology (NTNU) researchers have developed a promising antibiotic candidate against MRSA. Behind the discovery lies a methodology that may be important in the fight against antimicrobial ...
Cell & Microbiology
Dec 15, 2023
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36
A new study published in The Lancet Microbe has found that the transfer of antibiotic resistance genes between different bacteria is considerably more widespread than previously thought. The study is titled "Interphylum dissemination ...
Cell & Microbiology
Dec 7, 2023
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2
The field of epigenetics focuses on alterations in gene function that are inherited without changes in the DNA sequence, including histone modifications, post-translational modifications of amino acids, and covalent modifications ...
Molecular & Computational biology
Dec 6, 2023
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2
"What doesn't kill me makes me stronger," originally coined by Friedrich Nietzsche in 1888, is a perfect description of how bacteria develop antibiotic resistance.
Molecular & Computational biology
Nov 8, 2023
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1
As key regulators, pentatricopeptide repeat proteins (PPRs) function in ribonucleic acid (RNA) editing, organellar gene expression, photosynthesis, the organellar electron transport chain, cellular metabolism, and adenosine ...
Molecular & Computational biology
Oct 30, 2023
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27
A first-ever, atom-by-atom supercomputer simulation shows how antibiotics kill bacteria and illustrates other processes of the molecular machinery in living cells. The research opens fresh pathways to improving antibiotics, ...
Cell & Microbiology
Sep 20, 2023
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5
National University of Singapore (NUS) pharmaceutical scientists have successfully applied all-hydrocarbon-stapling modification to improve the enzymatic stability of their previously reported β-hairpin antimicrobial peptides ...
Biochemistry
Aug 14, 2023
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1
