A review delves into the significance of biomolecular condensation in cellular processes, the impact of aberrant phase separation on diseases such as neurodegenerative diseases, cancers, and infectious diseases, and the potential ...
Cell & Microbiology
May 16, 2024
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Computational chemist Mahmoud Moradi will develop enhanced, 3-D simulations of the molecular dynamics of coronavirus spike glycoproteins to gain better understanding of how the virus binds to human cells.
Biochemistry
Apr 15, 2020
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Scientists from China and Russia found a new way of searching for new drug candidates by inactivating the molecular structure of the human muscarinic receptor and applying screening to find drugs that it responds to. The ...
Biotechnology
Mar 11, 2020
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Hormones and other neurotransmitters, but also drugs, act upon receptors. "Their active substances bind to the receptors and modify the three-dimensional receptor arrangement regulating the downstream signal pathways," says ...
Biochemistry
Sep 6, 2018
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Potential drugs that seem promising in the lab, but don't show any activity in a person: they cost the industry an incredible amount of time and money. That's why Indira Nederpelt focuses on a more efficient search for new ...
Biochemistry
Apr 5, 2017
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Antigen receptors on B lymphocytes sense foreign molecules, such as pathogens or vaccines, and activate the B cells to produce antibodies that protect humans against many diseases. Prof. Dr. Michael Reth, Scientific Director ...
Cell & Microbiology
Sep 15, 2015
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Researchers at the Ruhr Universität Bochum have developed a new method for attaching proteins to the surface of germanium crystals – for the first time also membrane proteins. This enables time-resolved tracking of the ...
Materials Science
Mar 8, 2013
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The group of Prof. Dr. Ralf Erdmann at the Ruhr-Universität Bochum, Germany, discovered a connection of peroxisomal protein import and receptor export. In the Journal of Biological Chemistry, they disclosed that enzymes ...
Biochemistry
Feb 10, 2012
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From detecting pathogens in blood samples to the study of protein synthesis, Quartz Crystal Microbalance (QCM) sensors have many uses in modern biology. In this technique, antibodies anchored to gold electrodes on a piece ...
Optics & Photonics
Oct 31, 2011
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German researchers at the Ruhr-Universitaet have succeeded in controlling the activity of certain nerve cells using light, thus influencing the movements of mice. By changing special receptors in nerve cells of the cerebellum ...
Biochemistry
Jul 20, 2011
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