The protein p53 plays an essential role in the prevention of cancer by initiating the controlled death of a cell with damaged genes which is in danger to transform into a cancerous cell. The heat shock protein Hsp90, in turn, ...
Biotechnology
Sep 7, 2011
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A new study sheds light on a little understood biological process called quiescence, which enables blood-forming stem cells to exist in a dormant or inactive state in which they are not growing or dividing. According to the ...
Jan 9, 2009
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The p53 protein protects our cells from cancer and is an interesting target for cancer treatments. The problem is, however, that it breaks down rapidly in the cell. Researchers at Karolinska Institutet in Sweden have now ...
Biochemistry
Mar 14, 2022
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348
Many proteins work like Swiss Army knives, fitting multiple functions into their elaborately folded structures. A bit mysteriously, some proteins manage to multitask even with structures that are unfolded and floppy—"intrinsically ...
Cell & Microbiology
Jun 19, 2013
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Recent advances in imaging technology have made it possible to visualize intracellular dynamics, which offers a better understanding of several key biological principles for accelerating therapeutic development. Fluorescent ...
Biochemistry
Sep 8, 2022
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Even though it's almost impossible to see, computational biophysicist Rommie Amaro is using the Stampede supercomputer at the Texas Advanced Computing Center at The University of Texas at Austin to model the largest atomic ...
Biochemistry
Oct 27, 2016
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8
Before a malignant tumor develops, the immune system tries to fight against its altered proteins by producing certain cancer antibodies. A biosensor developed by scientists from the Complutense University of Madrid is able ...
Analytical Chemistry
Jan 12, 2017
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6
Investigators believe they have identified the founding member of a chemical family they hope will lead to a new class of cancer drugs, the first designed specifically against a childhood tumor, according to research led ...
Biochemistry
Mar 29, 2010
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To protect the health of future generations, body keeps a careful watch on its precious and limited supply of eggs. That's done through a key quality control process in oocytes (the immature eggs), which ensures elimination ...
Cell & Microbiology
Feb 17, 2011
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Biologists and chemists at the University of Konstanz have deciphered a molecular cellular mechanism related to the development of cancer. They report the interaction between the tumour-suppressor protein p53, known as the ...
Biotechnology
Jan 26, 2018
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