New modeling shows how synonymous mutations—those that change the DNA sequence of a gene but not the sequence of the encoded protein—can still impact protein production and function. A team of researchers led by Penn ...
Biochemistry
Dec 5, 2022
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15
A defense mechanism that human cells possess against viruses such as monkeypox, herpes simplex and human papillomavirus—all double-stranded DNA viruses—relies on proteins that patrol the cell, acting as sensors of the ...
Biotechnology
Nov 29, 2022
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39
The Plant Physiology and Biochemistry research team at the University of Konstanz has discovered previously unknown molecular mechanisms by which plants adapt to their environment—important basic knowledge in times of climate ...
Biochemistry
Nov 25, 2022
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47
The latest developmental drugs, particularly for use in oncology, rely on the targeted degradation of harmful pathogenic proteins. In a recent study published in Nature Chemical Biology, researchers at CeMM, the Research ...
Biochemistry
Nov 3, 2022
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32
Precise details of how a master regulator of gene expression binds its activating partner could open new avenues for cancer drug development.
Biochemistry
Oct 10, 2022
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82
Each day, millions of biological processes occur in our body at a cellular level. Studying these processes can help us learn more about how cells function, a field that has continued to intrigue researchers. Recently, however, ...
Biochemistry
Sep 30, 2022
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16
Nucleotide excision repair (NER) is a major conserved DNA repair pathway, which repairs various types of damage in the genome, such as those induced by ultraviolet light and environmental agents. Dysfunction in this pathway ...
Cell & Microbiology
Sep 27, 2022
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95
To better understand what drives biological diversity on Earth, scientists have historically looked at genetic differences between species. But this only provides part of the picture. The traits of a particular species are ...
Plants & Animals
Sep 9, 2022
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667
A team of researchers from the IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology) has designed in silico "molecular probes" able to track the progress of a protein that misbehaves in different neurodegenerative ...
Bio & Medicine
Sep 8, 2022
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30
The proteins that make up our cells hold within an entire world of information, which, when unlocked, can give us insights into the origins of many essential biological phenomena. This information is gathered using an analytical ...
Analytical Chemistry
Aug 4, 2022
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72
