On...off...on...off... The circuitry of insulin-releasing cells

A myriad of inputs can indicate a body's health bombard pancreatic beta cells continuously, and these cells must consider all signals and "decide" when and how much insulin to release to maintain balance in blood sugar, for ...

The hidden lives of proteins

An important Brandeis study appearing in the December 3 issue of Nature raises the curtain on the hidden lives of proteins at the atomic level. The study reports that for the first time, researchers used x-ray crystallography ...

Scientists identify first negative regulator of NOX4 translation

Nicotinamide adenine dinucleotide phosphate oxidase 4 (NADPH oxidase 4, NOX4) is an important member of the NADPH oxidase family that is primarily responsible for the production of H2O2. The regulation of NOX4 activity is ...

Protein from mosquitoes could help control dengue virus infection

NUS scientists have revealed the structure and function of a pupal cuticle protein found in the exoskeleton—a hard covering that supports and protects the bodies of some types of invertebrate animals, especially arthropods—of ...

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