Two years ago, the Zika virus drew attention to microcephaly, a developmental disorder in which the brain and skull display inhibited growth. But there are other causes of microcephaly, such as congenital genetic diseases. ...
Cell & Microbiology
Apr 24, 2017
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7
Durable repression of a gene that has a role in controlling cholesterol levels, achieved without permanent genome editing, has been demonstrated in a mouse study published in Nature this week.
Biotechnology
Feb 29, 2024
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16
Cellular processes are regulated through the balance between protein shapes that confer active or inactive functions. In the complexity of cellular regulations, the preferred shape (or conformation) of a protein often depends ...
Molecular & Computational biology
Sep 9, 2021
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26
For the first cell to develop into an entire organism, genes, RNA molecules and proteins have to work together in a complex way. At first, this process is indirectly controlled by the mother. At a certain point in time, the ...
Cell & Microbiology
Dec 6, 2022
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108
Researchers have identified over 5,700 new proteins in rice and are calling for a global effort to find the remaining missing proteins, in a new study co-authored by Macquarie University.
Biotechnology
Jan 9, 2019
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2
Nucleotide excision repair (NER) is a critical DNA repair pathway that plays a key role in maintaining transcription and genome integrity by removing bulky DNA lesions.
Cell & Microbiology
Dec 8, 2022
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71
Down syndrome, a congenital disorder stemming from abnormal cell division and differentiation, is most common in newborns fated to neurodevelopmental delays and other health complications.
Cell & Microbiology
Dec 19, 2023
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14
Metabolic reaction flux change is the final result of interacting regulations by intracellular gene expression, transcriptional regulation, protein level, translation modification, and allosteric effect. However, the regulatory ...
Cell & Microbiology
Jun 20, 2023
0
51
In any animal's lifecycle, the shift from egg cell to embryo is a critical juncture. This transition represents the formal initiation of development—a remarkably dynamic process that ultimately transforms a differentiated, ...
Cell & Microbiology
May 29, 2014
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0
Iron is essential for cells to function, but excess iron can damage cells. Accordingly, cells have sophisticated molecular mechanisms to constantly sense and adjust iron levels. Disorders of cellular iron metabolism affect, ...
Biochemistry
Sep 20, 2017
0
4
