Can something as simple as shape fully determine whether or not proteins will bind together? Scientists are commissioning supercomputers to find out.
Soft Matter
Aug 16, 2021
0
424
Two Skoltech researchers have presented a highly efficient neural network model that uses data on the structure of proteins to predict which of their parts interact with other biological molecules called peptides. Knowing ...
Biochemistry
Aug 9, 2021
0
1828
Proteins—long chains of amino acids—each play a unique role in keeping our cells and bodies functioning, from carrying out chemical reactions, to delivering messages, and protecting us from potentially harmful foreign ...
Molecular & Computational biology
Aug 3, 2021
0
790
Cells fight microbial invaders by engulfing them into membrane sacs—hostile environments in which pathogens are rapidly destroyed. However, the pathogen Salmonella enterica, which grows and reproduces inside cells, has ...
Cell & Microbiology
Jul 7, 2021
0
10
A new screening method that can test the effectiveness of therapeutic molecules designed to 'glue' proteins together in the body has been developed by researchers at the University of Birmingham and the University of Leicester.
Biochemistry
Jul 7, 2021
0
19
Synthetic biology offers a way to engineer cells to perform novel functions, such as glowing with fluorescent light when they detect a certain chemical. Usually, this is done by altering cells so they express genes that can ...
Biotechnology
Jul 2, 2021
1
208
The inhibition of pathological protein–protein interactions is a promising approach for treating a large number of diseases, including many forms of cancer. A team of researchers has now developed a bicyclic peptide that ...
Biochemistry
May 12, 2021
0
31
A research group led by Professor Xiang David Li from the Research Division for Chemistry and the Department of Chemistry, The University of Hong Kong, has developed a novel chemical tool for elucidating protein interaction ...
Molecular & Computational biology
Apr 27, 2021
0
5
Networks offer a powerful way to visualize and analyze complex systems. However, depending on the size and complexity of the network, many visualizations are limited. Protein interactions in the human body constitute such ...
Biotechnology
Apr 23, 2021
0
3
The creation of genes with new functions is a major driver of developmental innovation in all living organisms. How these genes acquire new functions over evolutionary time scales, however, is unclear.
Plants & Animals
Mar 29, 2021
0
48
