New tool enables mapping of protein interaction networks at scale

Proteins—long chains of amino acids—each play a unique role in keeping our cells and bodies functioning, from carrying out chemical reactions, to delivering messages, and protecting us from potentially harmful foreign ...

New insights into Salmonella's survival strategies

Cells fight microbial invaders by engulfing them into membrane sacs—hostile environments in which pathogens are rapidly destroyed. However, the pathogen Salmonella enterica, which grows and reproduces inside cells, has ...

Synthetic biology circuits can respond within seconds

Synthetic biology offers a way to engineer cells to perform novel functions, such as glowing with fluorescent light when they detect a certain chemical. Usually, this is done by altering cells so they express genes that can ...

Bicyclic protein mimetics inhibit the oncogene β-catenin

The inhibition of pathological protein–protein interactions is a promising approach for treating a large number of diseases, including many forms of cancer. A team of researchers has now developed a bicyclic peptide that ...

VR visualization supports research on molecular networks

Networks offer a powerful way to visualize and analyze complex systems. However, depending on the size and complexity of the network, many visualizations are limited. Protein interactions in the human body constitute such ...

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