A groundbreaking technique for in-depth mapping of protein localizations in whole tissue developed by researchers in the University at Buffalo School of Pharmacy and Pharmaceutical Sciences has been published in Nature Communications.
Biotechnology
Feb 2, 2023
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15
Researchers have visualized the protein binding site of the (pro)renin receptor known to be involved in pancreatic cancer development using an artificial intelligence-based protein structure prediction program. They predicted ...
Cell & Microbiology
Dec 9, 2022
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40
Today, most methods to determine the proteins inside a cell rely on a crude census—scientists usually grind a large group of cells up before characterizing their genetic material. But just as a population of 100 single ...
Biotechnology
Dec 6, 2022
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61
Coronaviruses have brought about three massive outbreaks in the past two decades. Each step of its life cycle invariably depends on the interactions among virus and host molecules. The interaction between virus RNA and host ...
Molecular & Computational biology
Nov 2, 2022
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4
What exactly are the molecular interactions between the virus causing COVID-19 and its human host? How might our genetic differences cause different disease courses? And how do still-emerging virus variants differ in their ...
Biotechnology
Oct 10, 2022
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101
Chemotherapy sucks. The treatments generally have awful side effects, and it's no secret that the drugs involved are often toxic to the patient as well as their cancer. The idea is that, since cancers grow so quickly, chemotherapy ...
Biochemistry
Aug 24, 2022
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119
Polymer brush films consists of monomer chains grown in close proximity on a substrate. The monomers, which look like "bristles" at the nanoscale, form a highly functional and versatile coating, such that it can selectively ...
Polymers
Aug 3, 2022
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124
Talin is a protein that controls cellular attachment and movement, but its malfunctioning also allows cancer cells to spread. DCL1 is a tumor-suppressing protein. But scientists don't fully understand how either protein works—or ...
Biotechnology
Jul 15, 2022
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137
A research group from Turku Bioscience Center, Finland, has developed a new method for studying the functionality of microbiota through metaproteomics. The new method shows broad potential for the study of microbiota on a ...
Biotechnology
Jul 6, 2022
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13
Oligonucleotides are short, single strands of synthetic DNA or RNA. Although they are small, these molecules play an important role in molecular and synthetic biology applications. One type of oligonucleotide—aptamers—can ...
Biotechnology
Jun 7, 2022
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68
