There are always exceptions to a rule, even one that has prevailed for more than three decades, as demonstrated by a Cold Spring Harbor Laboratory (CSHL) study on RNA splicing, a cellular editing process. The rule-flaunting ...
Biotechnology
May 17, 2012
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In order to use the CRISPR-Cas9 system to cut genes, researchers must design an RNA sequence that matches the DNA of the target gene. Most genes have hundreds of such sequences, with varying activity and uniqueness in the ...
Biotechnology
Oct 25, 2016
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A rare, small RNA turns a gene-splicing machine into a switch that controls the expression of hundreds of human genes. Howard Hughes Medical Institute Investigator and professor of Biochemistry Gideon Dreyfuss, PhD, and his ...
Cell & Microbiology
Aug 21, 2013
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2
A collaborative study by the UTokyo-KI LINK program, headed by Camilla Björkegren from Karolinska Institutet, Kristian Jeppsson and Katsuhiko Shirahige from The University of Tokyo shows that a protein complex named Smc5/6 ...
Cell & Microbiology
Jan 31, 2024
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56
A team of University of Georgia researchers has developed a new way to breed plants with better traits. By introducing a human protein into the model plant species Arabidopsis thaliana, researchers found that they could selectively ...
Biotechnology
Mar 6, 2018
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Even fans of black-and-white film can't deny that color brought new life to photography and motion pictures. And when it comes to learning what happens inside the body, there's no substitute for color. Were it possible, for ...
Biotechnology
Jan 31, 2022
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157
Scientists of Helmholtz Zentrum München and Ludwig-Maximilians-Universität Munich (LMU) have discovered that two new classes of histone modifications couple cellular metabolism to gene activity. The study was published ...
Cell & Microbiology
Oct 24, 2017
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Researchers at the Max Delbrueck Center for Molecular Medicine (MDC) have identified an epigenetic mechanism that appears to strongly influence healthy aging. It's a protein that controls muscle integrity, lifespan and levels ...
Cell & Microbiology
Aug 9, 2019
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a field that describes how genes may be regulated without altering the underlying DNA itself—scientists are deciphering the many ways in which enzymes act on the proteins surrounding DNA within cells.
Biochemistry
Jan 20, 2011
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Within the cells, the RNA polymerase (RNAP) protein complex clutches DNA like a crab claw, scanning across gene-coding regions and transcribing these sequences into the messenger RNA molecules that will ultimately provide ...
Cell & Microbiology
Mar 4, 2011
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