Proteins are the workhorses of the cell and thus responsible for almost all biological functions including metabolism, signal transmission or the determination of the cell's shape. However, before they can fulfill their various ...
Cell & Microbiology
May 9, 2014
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(Phys.org) —JILA researchers have engineered a short, flexible, reusable probe for the atomic force microscope (AFM) that enables state-of-the-art precision and stability in picoscale force measurements. Shorter, softer ...
Nanophysics
Apr 9, 2014
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Scientists at The Scripps Research Institute (TSRI) have invented small-molecule folding probes that enable them to quantify functional, normally folded and disease-associated misfolded conformations (shapes) of a protein-of-interest ...
Cell & Microbiology
Mar 4, 2014
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An ancient chemical, present for billions of years, appears to have helped proteins function properly since time immemorial.
Cell & Microbiology
Feb 20, 2014
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Scientists using sophisticated imaging techniques have observed a molecular protein folding process that may help medical researchers understand and treat diseases such as Alzheimer's, Lou Gehrig's and cancer.
Cell & Microbiology
Jun 28, 2013
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(Phys.org) —In chemical reactions, left and right can make a big difference. A "left-handed" molecule of a particular chemical composition could be an effective drug, while its mirror-image "right-handed" counterpart could ...
Nanophysics
Jun 27, 2013
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New research from Rice University, Baylor College of Medicine (BCM) and the Puget Sound Blood Center (PSBC) has revealed how stresses of flow in the small blood vessels of the heart and brain could cause a common protein ...
General Physics
Mar 5, 2013
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When proteins get "out of shape", the consequences can be fatal. They lose their function and in some cases form insoluble, toxic clumps that damage other cells and can cause severe diseases such as Alzheimer's or Parkinson's. ...
Biochemistry
Feb 11, 2013
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(Phys.org)—Cornell researchers have discovered that a protein known for moving cells around in the body also helps regulate a cellular organelle responsible for generating one-third of all proteins in the human body.
Cell & Microbiology
Dec 21, 2012
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(Phys.org)—Acidity (pH) and its changes play an important role in many physiological processes, including protein folding, and can act as indicators of cancer. In the journal Angewandte Chemie, American researchers have ...
Nanomaterials
Dec 14, 2012
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