Desmoplakin's tail gets the message

Cells control the adhesion protein desmoplakin by modifying the tail end of the protein, and this process goes awry in some patients with arrhythmogenic cardiomyopathy, according to a study in The Journal of Cell Biology.

Watching nanoscale assembly live

Ebola virus, Alzheimer's amyloid fibrils, tissue collagen scaffolds and cellular cytoskeleton are all filamentous structures that spontaneously assemble from individual proteins.

How cells get a skeleton

The mechanism responsible for generating part of the skeletal support for the membrane in animal cells is not yet clearly understood. Now, Jean-François Joanny from the Physico Chemistry Curie Unit at the Curie Institute ...

A trick to fold proteins more quickly

A team of researchers of the International School for Advanced Studies (SISSA) of Trieste and of University of Cambridge have devised a method to reduce the time used to simulate how proteins take on their signature three-dimensional ...

Molecular assembly line brings muscles into shape

Scientists at the Research Institute of Molecular Pathology (IMP) in Vienna, Austria and at the University of Cologne, Germany have discovered the molecular basis underlying the patterned folding and assembly of muscle proteins. ...

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