Working proteins make good use of frustration
Proteins fold according to a script written in the pattern of their amino acids. But to function properly, some parts must ad-lib.
Proteins fold according to a script written in the pattern of their amino acids. But to function properly, some parts must ad-lib.
Biochemistry
Feb 11, 2019
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Protein activity is strictly regulated. Incorrect or poor protein regulation can lead to uncontrolled growth and thus cancer or chronic inflammation. Members of the Institute of Veterinary Biochemistry and Molecular Biology ...
Cell & Microbiology
Mar 10, 2013
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Inhibiting a molecular process cells use to direct proteins to their proper destinations causes more than 90 percent of affected mosquitoes to die within 48 hours of blood feeding, a UA team of biochemists found.
Biochemistry
Jul 18, 2011
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One of the biggest questions facing scientists today is how life began. How did non-living molecules come together in that primordial ooze to form the polymers of life? Scientists at the Georgia Institute of Technology have ...
Cell & Microbiology
Mar 8, 2010
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RNA, or ribonucleic acid, is present in the cells of all living beings and required to synthesize proteins. A research team at the University of California, Riverside, has discovered the structure of a novel RNA-modifying ...
Molecular & Computational biology
Nov 6, 2019
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424
(PhysOrg.com) -- When a cell divides, the genetic information in the chromosomes must be passed on error-free to the daughter cells. Researchers at the Friedrich Miescher Laboratory in Tübingen are studying this process ...
Cell & Microbiology
Jun 30, 2011
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In multicellular organisms, there are three types of protein glycosylation. N-glycosylation, O-mannosylation and C-mannosylation. All of these processes take place in the endoplasmic reticulum, and in all of them enzymes ...
Biochemistry
Jan 16, 2023
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(PhysOrg.com) -- An oxygen-sensitive enzyme has been found to play a key role in how genes create the many different proteins that make up our bodies.
Biochemistry
Jul 3, 2009
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(PhysOrg.com) -- UC Irvine researchers have discovered that circadian rhythms - our own body clock - regulate energy levels in cells. The findings have far-reaching implications, from providing greater insights into the bond ...
Cell & Microbiology
Mar 12, 2009
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Open an undergraduate biochemistry textbook and you will learn that enzymes are highly efficient and specific in catalyzing chemical reactions in living organisms, and that they evolved to this state from their "sloppy" and ...
Biochemistry
Aug 30, 2012
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