Breakthrough in understanding role of enzyme in disease

Researchers at the University of Dundee have uncovered the mechanism of an important human enzyme that plays a role in the development of debilitating diseases including cancer, dementia and diabetes.

Small enzyme-mimicking polymers may have helped start life

Most effort in origins of life research is focused on understanding the prebiotic formation of biological building blocks. However, it is possible early biological evolution relied on different chemical structures and processes, ...

Chemists bring mixed folded proteins to life

Scientists from ITMO University in Saint Petersburg and Hebrew University in Jerusalem have found a way to recover a protein structure after its chemical denaturation. The method is based on electrostatic interaction between ...

Structure of protein nanoturbine revealed

Cells rely on protein complexes known as ATP synthases or ATPases for their energy needs. Adenosine triphosphate (ATP) molecules power most of the processes sustaining life. Structural biologist Professor Leonid Sazanov and ...

New theories and materials aid the transition to clean energy

With each passing day, the dark side of our addiction to fossil fuels becomes more apparent. In addition to slashing emissions of carbon dioxide, society must find sustainable alternatives to power the modern world.

Scaling laws in enzymes may help predict life 'as we don't know it'

The only references we have for "life" are the forms we know on Earth. Astrobiologists suspect that the search for alien life, and even for the origins of life on Earth, may require a broader scope. A NASA-funded team of ...

Iron-sulfur enzymes as candidates for antibiotic development

The iron-sulfur protein IspH plays a central role in the terpene metabolism of several pathogens. The mechanism of the reaction provides an approach for developing new antibiotics, particularly against malaria and tuberculosis. ...

Researchers develop tool to drastically speed up the study of enzymes

For much of human history, animals and plants were perceived to follow a different set of rules than the rest of the universe. In the 18th and 19th centuries, this culminated in a belief that living organisms were infused ...

page 4 from 31