Gene editing is one of the latest breakthroughs in biology. The widely known CRISPR-Cas gene editing system provided prokaryotes (organisms that lack cell nuclei) an immunity against foreign DNA. Since the discovery of the ...
Cell & Microbiology
Apr 7, 2023
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56
A new artificial intelligence tool can predict the functions of enzymes based on their amino acid sequences, even when the enzymes are unstudied or poorly understood. The researchers said the AI tool, dubbed CLEAN, outperforms ...
Biotechnology
Mar 30, 2023
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923
Scientists at the U.S. Department of Energy's Brookhaven National Laboratory have produced the first atomic-level structure of an enzyme that selectively cuts carbon-hydrogen bonds—the first and most challenging step in ...
Biotechnology
Mar 30, 2023
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9
Researchers from Facebook AI Research (FAIR) at Meta AI have published a paper in the journal Science detailing a machine-learning-created database of 617 million predicted protein structures. The ESMFold language model described ...
In a study published in The Plant Cell, researchers led by Li Yunhai at the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences described a role for the endoplasmic reticulum (ER)–associated ...
Cell & Microbiology
Feb 10, 2023
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22
Scientists have created an AI system capable of generating artificial enzymes from scratch. In laboratory tests, some of these enzymes worked as well as those found in nature, even when their artificially generated amino ...
Biotechnology
Jan 26, 2023
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242
In multicellular organisms, there are three types of protein glycosylation. N-glycosylation, O-mannosylation and C-mannosylation. All of these processes take place in the endoplasmic reticulum, and in all of them enzymes ...
Biochemistry
Jan 16, 2023
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84
Enzymes have the potential to transform the chemical industry by providing green alternatives to a slew of processes. These proteins act as biological catalysts, and with the help of molecular engineering, they can make naturally ...
Biochemistry
Jan 12, 2023
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50
Genetic information encoded in genomic DNA is transcribed to mRNAs and then the codons on mRNA are decoded by transfer RNAs (tRNAs) during protein synthesis. tRNAs deliver amino acids to ribosomes and proteins are synthesized ...
Biochemistry
Dec 27, 2022
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68
After an intrepid, decade-long search, Johns Hopkins Medicine scientists say they have found a new role for a pair of enzymes that regulate genome function and, when missing or mutated, are linked to diseases such as brain ...
Cell & Microbiology
Dec 22, 2022
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25
