Scientists create potent 'degrader' of cancer-driving protein
Scientists at The Institute of Cancer Research, London, have created a compound that destroys a protein involved in driving cancers, including B-cell lymphoma.
Scientists at The Institute of Cancer Research, London, have created a compound that destroys a protein involved in driving cancers, including B-cell lymphoma.
Biochemistry
Apr 26, 2023
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51
Development of vaccines against SARS-CoV-2 has been rapid, but the rise of variants forces scientists to frequently modify treatments. Ideally, therapies would target mutation-resistant viral proteins, but this has proven ...
Biochemistry
Apr 26, 2023
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44
CycPeptMPDB, a novel database created by Tokyo Tech researchers, focuses on the membrane permeability of cyclic peptides and could accelerate the development of drugs based on these promising compounds. This database was ...
Biochemistry
Apr 5, 2023
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36
With the release of platforms like DALL-E 2 and Midjourney, diffusion generative models have achieved mainstream popularity, owing to their ability to generate a series of absurd, breathtaking, and often meme-worthy images ...
Biochemistry
Mar 31, 2023
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72
Shigella bacteria can infect humans but not mice. In the March 29 issue of Nature, a team from UConn Health explains why. Their findings may explain the multifariousness of a key weapon of our immune system.
Cell & Microbiology
Mar 30, 2023
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20
Have a cough, sore throat and congestion? Any number of respiratory viruses could be responsible. Conventional tests can identify certain likely culprits by relying on chemical reactions, but some researchers want to swap ...
Analytical Chemistry
Mar 28, 2023
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The rapid spread of COVID-19 may have been partly due to changes in the structure of the SARS-CoV-2 virus wrought by an early mutation in its genome, a detailed analysis by RIKEN researchers suggests. The finding, published ...
Molecular & Computational biology
Mar 27, 2023
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55
The highly contagious canine distemper virus is dangerous to dogs and wild life animals. It is also closely related to the equally highly contagious measles virus. Researchers at the University of Bern and the Zurich University ...
Molecular & Computational biology
Mar 15, 2023
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74
One of the most expensive steps in manufacturing protein drugs such as antibodies or insulin is the purification step: isolating the protein from the bioreactor used to produce it. This step can account for up to half of ...
Bio & Medicine
Feb 28, 2023
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165
A team of researchers has developed a new method to screen FDA-approved drugs to determine if they could be repurposed or improved to help patients with a rare, debilitating disease of the nervous system.
Biochemistry
Feb 16, 2023
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24