It's a dogma taught in every introductory biology class: Proteins are composed of combinations of 20 different amino acids, arranged into diverse sequences like words. But researchers trying to engineer biologic molecules ...
Biotechnology
13 hours ago
0
65
Researchers from the University of Cincinnati College of Medicine and Cincinnati Children's Hospital have found a new method to increase both speed and success rates in drug discovery.
Biochemistry
Aug 30, 2024
0
66
Researchers at the Center for Algorithmic and Robotized Synthesis within the Institute for Basic Science have taken a significant step forward in understanding the stability of proteins by leveraging the power of AI.
Molecular & Computational biology
Aug 29, 2024
0
1
One in every three FDA-approved drugs targets a single superfamily of receptors dotting the surfaces of human cells. From beta blockers to antihistamines, these essential, life-saving medications trigger winding biochemical ...
Biochemistry
Aug 27, 2024
0
17
All organisms—from fungi to mammals—have the capacity to evolve and adapt to their environments. But viruses are master shapeshifters with an ability to mutate greater than any other organism. As a result, they can evade ...
Cell & Microbiology
Aug 27, 2024
0
55
Molecular glues are typically small chemical molecules that act on the interface between the target protein and the degradation machinery to trigger ternary complex formation. Identification of molecular glues is challenging, ...
Molecular & Computational biology
Aug 22, 2024
0
1
A new artificial intelligence model developed by USC researchers and published in Nature Methods can predict how different proteins may bind to DNA with accuracy across different types of protein, a technological advance ...
Molecular & Computational biology
Aug 9, 2024
0
52
Artificial intelligence (AI) can help identify molecules that could serve as new drugs for mental health disorders. AI can be used to predict the three-dimensional structures of important receptors and thereby speed up the ...
Biotechnology
Aug 8, 2024
0
16
The human body contains at least 20,000 different proteins, often called the "workhorses of the cell" because of their role in keeping cells healthy. Each protein consists of a unique string of amino acids that affects its ...
Biotechnology
Aug 2, 2024
0
19
In a new study, a multinational research team led by Dr. Adnan Sljoka (RIKEN) and Prof. Akio Kitao (Tokyo Tech), in collaboration with Prof. Scott Prosser (University of Toronto), has carried out experimental and computational ...
Cell & Microbiology
Aug 1, 2024
0
22
