The search for new drug compounds is probably worse than looking for a needle in a haystack because scientists are limited in the size of the haystacks they can rummage through—time and money make it virtually impossible ...
Other
Feb 1, 2010
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(PhysOrg.com) -- Researchers have learned the atomic-scale arrangement of proteins in a structure that enables a virus to invade and fuse with host cells, showing precisely how the structure morphs with changing acidity to ...
Cell & Microbiology
Dec 1, 2010
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(Phys.org) —Every available cancer drug is susceptible to resistance, according to Mansoor Amiji, Distinguished Professor and chair of the Department of Pharmaceutical Sciences. Tumors grow more quickly than blood vessels, ...
Bio & Medicine
Mar 19, 2013
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Understanding the structure of proteins is a vital first step in developing new drugs, but to date, researchers have had difficulty studying the large number of proteins that are normally embedded in the cell membrane, a ...
Bio & Medicine
Jul 24, 2009
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An antibiotic called thanatin attacks the way the outer membrane of Gram-negative bacteria is built. Researchers at the University of Zurich have now found that this happens through a previously unknown mechanism. Thanatin, ...
Biochemistry
Nov 15, 2018
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245
A collaborative team led by a Northeastern University professor may have altered the way we look at drug development for HIV by uncovering some unusual properties of a human protein called APOBEC3G (A3G).
Biochemistry
Nov 25, 2013
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Chemists at The Scripps Research Institute (TSRI) have devised a new technique for connecting drug molecules to antibodies to make advanced therapies.
Biochemistry
Oct 7, 2013
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0
A tiny but unexpected change to a segment of RNA in a single-cell organism looks a lot like a mistake, but is instead a change to the genetic information that is essential to the organism's survival.
Cell & Microbiology
Oct 3, 2013
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0
Predicting a protein's location within a cell can help researchers unlock a plethora of biological information that's critical for developing future scientific discoveries related to drug development and treating diseases ...
Molecular & Computational biology
Jun 2, 2023
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63
Synthetic proteins have been created that move in response to their environment in predictable and tunable ways. These motile molecules were designed from scratch on computers, then produced inside living cells.
Biochemistry
May 16, 2019
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