Degrading viral RNA to treat SARS-CoV-2 infection

Development of vaccines against SARS-CoV-2 has been rapid, but the rise of variants forces scientists to frequently modify treatments. Ideally, therapies would target mutation-resistant viral proteins, but this has proven ...

Study describes mechanism that regulates activity of memory gene

The protein PKMzeta is known to be associated with long-term memory formation. Neurological disorders such Alzheimer's disease, as well as depression and aging, correlate with reduced levels of this protein in the brain. ...

Speeding up drug discovery with diffusion generative models

With the release of platforms like DALL-E 2 and Midjourney, diffusion generative models have achieved mainstream popularity, owing to their ability to generate a series of absurd, breathtaking, and often meme-worthy images ...

New targeting opportunities discovered against canine distemper virus

The highly contagious canine distemper virus is dangerous to dogs and wild life animals. It is also closely related to the equally highly contagious measles virus. Researchers at the University of Bern and the Zurich University ...

A novel biosensor to detect DNA damage in real time

Double-strand breaks (DSBs) are a type of DNA damage where both strands of DNA break at the same location. They can adversely affect cell growth and functioning. Currently, DSBs are detected by immunostaining techniques, ...

New purification method could make protein drugs cheaper

One of the most expensive steps in manufacturing protein drugs such as antibodies or insulin is the purification step: isolating the protein from the bioreactor used to produce it. This step can account for up to half of ...

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