Understanding light-activated proteins in order to improve them

Today, proteins that can be controlled with light are a widely used tool in research to specifically switch certain functions on and off in living organisms. Channelrhodopsins are often used for the technique known as optogenetics: ...

Inside the protein channel that keeps bacteria alive

Almost all bacteria rely on the same emergency valves—protein channels that pop open under pressure, releasing a deluge of cell contents. It is a last-ditch effort, a failsafe that prevents bacteria from exploding and dying ...

Modulating cells' chloride channels

Laboratory cell experiments and computer simulations have revealed molecular mechanisms regulating a protein channel responsible for transporting chloride and other charged molecules across cell membranes. The findings were ...

Chemists discover the structure of a key coronavirus protein

MIT chemists have determined the molecular structure of a protein found in the SARS-CoV-2 virus. This protein, called the envelope protein E, forms a cation-selective channel and plays a key role in the virus's ability to ...

How plants shut the door on infection

Plants have a unique ability to safeguard themselves against pathogens by closing their pores—but until now, no one knew quite how they did it. Scientists have known that a flood of calcium into the cells surrounding the ...

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