A molecular biologist at the University of Massachusetts Amherst who has for decades studied the nightmarish group of fatal diseases caused by prions—chronic wasting disease in deer, mad cow in cattle and its human analog—credits ...
Molecular & Computational biology
May 6, 2020
0
162
Many neurodegenerative diseases are characterized by proteins that assume an abnormal configuration, which leads to their aggregation and deposition in and around rve cells, causing cell death. This process, called amyloid ...
Biochemistry
May 4, 2011
0
1
New research results from Uppsala University, Sweden, show that the key to treating neurodegenerative prion diseases such as mad cow disease and Creutzfeldt-Jakob disease may lie in the ribosome, the protein synthesis machinery ...
Biochemistry
Jul 2, 2013
0
0
Separating target molecules in biological samples is a critical part of diagnosing and detecting diseases. Usually the target and probe molecules are mixed and then separated in batch processes that require multiple pipetting, ...
Biochemistry
Sep 17, 2013
0
0
Medical researchers at the University of Alberta have made a discovery that may explain how prion diseases, like chronic wasting disease and mad cow disease, adapt in order to spread between various types of animals.
Biochemistry
Mar 11, 2013
1
0
Workhorse molecules called heat-shock proteins contribute to refolding proteins that were once misfolded and clumped, causing such disorders as Parkinson's disease, amyotrophic lateral sclerosis, and Alzheimer's disease. ...
Cell & Microbiology
Jan 22, 2015
0
60
The central nervous systems of humans and cattle alike are attacked by prions (abnormal insoluble amyloidogenic proteins) when they suffer from Creutzfeldt–Jakob disease (CJD) or bovine spongiform encephalopathy (BSE).
Biochemistry
Mar 21, 2011
0
0
A short segment of an infectious protein known as a prion protein plays a crucial role in determining how susceptible the protein is to interspecies prion transmission, RIKEN researchers have discovered in a yeast study. ...
Cell & Microbiology
Jul 17, 2020
0
31
Prions, the much-maligned proteins most commonly known for causing "mad cow" disease, are commonly used in yeast to produce beneficial traits in the wild. Moreover, such traits can be passed on to subsequent generations and ...
Cell & Microbiology
Feb 15, 2012
0
0
(Phys.org) —3D structures of biological molecules like proteins directly affect the way they behave in our bodies. EPFL scientists have developed a new infrared-UV laser method to more accurately determine the structure ...
Biochemistry
May 13, 2013
0
0
