Keeping chromosomes in check: A new role for heterochromatin

Although many people are aware that chromosomal damage and shortening contribute to the aging process, understanding how chromosomal defects occur is about more than just finding a way to turn back the clock. Large changes ...

Enzyme structure reveals how DNA is opened up for transcription

DNA is a molecular manual that contains instructions for building life. And, like any manual, DNA isn't all that useful if it remains unopened and unread. In order to transcribe DNA, the enzyme RNA polymerase, or RNAP, must ...

Researchers study DNA polymerases at the molecular level

Complex biological systems can be described as a network of chemical processes that take place in molecules. The scientists of the "ChemLife" research initiative at the University of Konstanz are working together in an equally ...

DNA-based method detects trace amounts of peanut in foods

For people with severe peanut allergies, eating even miniscule amounts of the legume can trigger anaphylaxis —- a life-threatening condition characterized by dizziness, breathing difficulties and, sometimes, loss of consciousness. ...

Study reveals how enzyme detects ultraviolet light damage

Damage to DNA is a constant threat to cellular life, and so it is constantly monitored and detected by a family of enzymes called RNA polymerases, resulting in subsequent repair to maintain genome integrity. In a paper published ...

CRISPR diversifies: Cut, paste, on, off, and now—evolve

Life is astoundingly diverse. By taking antibiotics to stop infections or using yeast to brew beer, we are co-opting useful products and processes that evolved naturally. But what happens when the trait we want can't be found ...

page 3 from 23