A group of rare diseases called "ciliopathies"—polycystic kidney disease notable among them—emerge from defects in cilia, the tiny hair-like structures on the surface of almost every cell type. But the specific molecular-level ...
Cell & Microbiology
Apr 27, 2022
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60
Although the cilium has been known to scientists for more than 100 years, it is only recently that it has been acknowledged to play important roles in physiology. Virtually every cell has a primary cilium that functions to ...
Biochemistry
Nov 25, 2019
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32
Nonsense mutations are single-letter errors in the genetic code that prematurely halt the production of critical proteins. These unfinished proteins are unable to function normally, and nonsense mutations cause 10-15 percent ...
Molecular & Computational biology
Feb 19, 2019
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45
In an article published online ahead of print on Feb. 19, 2015 in the Journal of Biological Chemistry (JBC), investigators at the Medical University of South Carolina (MUSC) and the Ralph H. Johnson VA Medical Center report ...
Biochemistry
Mar 17, 2016
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10
Many of our cells are equipped with a hairlike "antenna" that relays information about the external environment to the cell, and scientists have already discovered that the appearance and disappearance of these so-called ...
Cell & Microbiology
Jan 12, 2017
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7
Scientists at Johns Hopkins Medicine and the National Tsing Hua University in Taiwan say they have found a fast way to manipulate a cell's cilia, the tiny, fingerlike protrusions that "feel" and sense their microscopic environment. ...
Cell & Microbiology
May 15, 2018
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24
A team of scientists from Singapore and France has revealed the underlying mechanism for the formation and growth of a fundamental type of tissue – epithelial tubes. Defects in the architecture of epithelial tubes lead ...
Cell & Microbiology
Feb 24, 2016
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12
You've never seen cilia like these before. Brandeis University researchers have developed a new model to study these tiny but vital cellular structures with more clarity and detail than ever before, providing a clearer picture ...
Cell & Microbiology
Mar 27, 2014
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