Smart drug design to prevent malaria treatment resistance
Malaria treatment resistance could be avoided by studying how resistance evolves during drug development, according to a new paper published in Cell Chemical Biology.
Malaria treatment resistance could be avoided by studying how resistance evolves during drug development, according to a new paper published in Cell Chemical Biology.
Biochemistry
May 9, 2019
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22
Scientists at the Institute of Genome Sciences (IGS) at the University of Maryland School of Medicine (UMSOM) have developed a novel way with genome sequences to study and better understand transmission, treat and ultimately ...
Biotechnology
Feb 8, 2019
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An international research team led by scientists at the University of California, Riverside, and the La Jolla Institute for Immunology has found that malaria parasite genomes are shaped by parasite-specific gene families, ...
Cell & Microbiology
Feb 4, 2019
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173
An international team led by Institute researchers has visualised the unique molecular 'key' used by the world's deadliest malaria parasite, Plasmodium falciparum, to enter and infect human blood cells.
Cell & Microbiology
Dec 13, 2018
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105
A study led by the Barcelona Institute for Global Health (ISGlobal) reveals a new mechanism by which the malaria parasite Plasmodium falciparum converts from its asexual to its sexual form, which can be transmitted to the ...
Plants & Animals
Nov 27, 2018
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35
Malaria is the most prevalent blood-borne infectious disease caused by parasites of the species Plasmodium. In 2016, more than 216 million malaria infections were reported resulting in 445,000 deaths across the developing ...
Cell & Microbiology
Oct 10, 2018
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Malaria remains an economic and health burden to the developing world. As plasmodium, the causative agent of malaria, is acquiring rapid resistance against currently used drugs, identification of new classes of anti-malarials ...
Biochemistry
Oct 10, 2018
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Malaria remains a significant threat to human health with approximately 216 million cases annually and over 400,000 deaths worldwide. It is caused by the Plasmodium parasite, which has a complex lifecycle involving transmission ...
Cell & Microbiology
Sep 4, 2018
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The genome sequences of ape parasites related to Plasmodium vivax (P. vivax), the main source of mosquito-borne malaria outside Africa, provide insights on the origin and early evolution of the human parasite. This finding ...
Cell & Microbiology
Aug 20, 2018
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The vacuole, a compartment inside human red blood cells in which malaria parasites reproduce and develop, takes on a distinct spherical shape just minutes before its membrane ruptures, leading to the release of parasites ...
Cell & Microbiology
Jul 12, 2018
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4