Plasmids, which are DNA molecules capable of independent replication in cells, have played an important role in gene technology. Researchers from Uppsala University in Sweden have now demonstrated that plasmid-based methods, ...
Biotechnology
Nov 6, 2009
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Researchers from Konstantin Severinov's laboratory have shown what luck has to do with bacterial cells acquiring and retaining small DNA molecules called plasmids in spite of the countering action of the CRISPR-Cas defense. ...
Evolution
May 6, 2022
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Conjugative plasmids are extrachromosomal genetic elements that carry genetic determinants for adaptive traits. They contribute to the global dissemination of antibiotic resistance among multidrug-resistant pathogenic bacteria.
Cell & Microbiology
Jan 25, 2021
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Genetic variations, such as mutations, recombinations, or transpositions occur naturally in cultured microorganisms and are often considered nonneutral mutations.
Cell & Microbiology
Mar 6, 2023
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Genetic analysis of an outbreak of drug-resistant infections in one institution shows an unprecedented level of transference of resistance among strains and even species of bacteria. Researchers from the University of Virginia ...
Cell & Microbiology
Jan 4, 2012
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As a key global enabler of the revolutionary genome editing technology known as CRISPR, the nonprofit organization Addgene has made available more than 100,000 CRISPR plasmids (circular DNA fragments) to 3,400 laboratories ...
Biotechnology
Jun 18, 2018
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Researchers at Karolinska Institutet are introducing a new gold standard quality-control tool for counting of mRNA molecules in single cell sequencing. The new method is described in the journal Nature Methods.
Biotechnology
Jun 3, 2022
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18
A team of investigators has isolated colistin-resistant Escherichia coli from a commercial poultry farm in China. Colistin is an antibiotic of last resort against certain bacteria. The research is published May 14 in Antimicrobial ...
Cell & Microbiology
May 14, 2018
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In the gastrointestinal tract of host animals, bacteria can exchange the genes responsible for antibiotic resistance (AR) via small, circular chunks of DNA called plasmids. However, the process in this complex environment ...
Cell & Microbiology
Jan 29, 2020
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5
Though the harnessing of antibiotics is one of the most significant human innovations, their efficacy is continuously eroded by the craftiness of their microbial targets. Once a single bacterium mutates to become resistant ...
Cell & Microbiology
Jan 16, 2023
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