"The strategy was to design the drug to be able to hook into the hole of the FTase and GGTase I, otherwise the surface of the proteins are too large and slippery," Dr. Junko Ohkanda of Shinshu University explains her strategy ...
Biochemistry
Sep 24, 2019
0
7
Researchers at EPFL and the University of Bern have developed a groundbreaking method for studying the electrical signals of cardiac muscle cells. The technology has numerous potential applications in basic and applied research—such ...
Bio & Medicine
Sep 4, 2019
0
38
Drug-resistant bacteria responsible for deadly hospital-acquired infections shut out antibiotics by closing tiny doors in their cell walls.
Cell & Microbiology
Sep 2, 2019
0
427
Scientists at EPFL have developed a new method to synthesize and screen thousands of macrocyclic compounds, a family of chemicals that are of great interest in the pharmaceutical industry. The study is published in Science ...
Materials Science
Aug 21, 2019
0
55
A new study in Environmental Toxicology and Chemistry takes a harder look at the effects a common anti-inflammatory medication and its degradation products have on amphibians. There have been many studies that review the ...
Ecology
Aug 12, 2019
0
21
Limonoids are a class of plant natural products whose complex chemistry has been intensively investigated for over 50 years.
Biotechnology
Aug 2, 2019
1
60
Homeowners who rely on private wells as their drinking water source can be vulnerable to bacteria, nitrates, and other contaminants that have known human health risks. Because they are not connected to a public drinking water ...
Environment
Jul 24, 2019
0
12
An international collaboration of chemists from Tomsk Polytechnic University, USA, Great Britain, Canada, Belgium, and France has developed a line of polyvalent iodine-based reagents for organic synthesis. This is an eco-friendly ...
Materials Science
Jul 8, 2019
0
0
A new form of crystalline lactose has been discovered using part of the technique that gives UK chocolate its unique appeal.
Materials Science
Jul 8, 2019
0
0
Researchers at the University of Illinois at Chicago and AbbVie Inc. have developed a novel device that will help scientists and pharmaceutical companies more effectively screen and test formation of drug substance—active ...
Analytical Chemistry
Jun 26, 2019
0
0
