Homogeneous hydrogenolysis with molecular palladium

Tritium 3H, a radioactive isotope of hydrogen, is commonly used in medicinal chemistry as a label to follow the course of a drug in the human body. Chemists like to use the technique to evaluate drug candidates and their ...

Nobel in chemistry honors 'greener' way to build molecules

Two scientists won the Nobel Prize in chemistry Wednesday for finding an ingenious and environmentally cleaner way to build molecules—an approach now used to make a variety of compounds, including medicines and pesticides.

Genome mining leads to a new type of peptide prenylation

Researchers from NUS used a genome mining approach to identify a new cyclic peptide (tolypamide) derived from a cyanobacterium. The biosynthesis of tolypamide features a new type of enzyme that is able to prenylate a range ...

Researchers access both enantiomers by varying reaction time

Homochirality is a fundamental feature of all living organism. It is well known that a pair of enantiomers of chiral drug molecules, whose structures have a non-superimposable mirror-image relationship to each other, will ...

3-D printing with applications in the pharmaceutical industry

University of Seville researchers, in collaboration with the University of Nottingham, have managed to create the first image of nanoparticles of stabilised gold with biodegradable and biocompatible systems that have been ...

Chemists invent new Lewis acidity test using fluorescence

York University chemists have invented a new fluorescence-based method for accurately determining the strength of a range of Lewis acids, which could one day be used to help purify pharmaceutical drugs, improve industrial ...

How AI could spur drug development

Using artificial intelligence in drug design would give pharmaceutical research a boost, says Gisbert Schneider. In the medium term, computers could even carry out experiments autonomously.

Tailor-made synthesis of cyclic chemicals by means of enzymes

Penicillin-based antibiotics contain a five-membered hydrocarbon cycle, additionally incorporating a sulfur and a nitrogen atom. Nadine Zumbrägel, doctoral student at the Chair of Organic Chemistry I at Bielefeld University, ...

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