(PhysOrg.com) -- A new biophysical and biochemical study may lead to better understanding of how structural flexibility controls the interaction of a protein that is closely involved with cancer, aging and other chronic diseases ...
Biochemistry
Apr 13, 2011
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The gene for the protein p53 is the most frequently mutated in human cancer. It encodes a tumor suppressor, and traditionally researchers have assumed that it acts primarily as a regulator of how genes are made into proteins. ...
Cell & Microbiology
Mar 2, 2011
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Like a bounty hunter returning escapees to custody, a cancer-fighting gene converts organ cells that change into highly mobile stem cells back to their original, stationary state, researchers report online at Nature Cell ...
Cell & Microbiology
Feb 25, 2011
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Investigators believe they have identified the founding member of a chemical family they hope will lead to a new class of cancer drugs, the first designed specifically against a childhood tumor, according to research led ...
Biochemistry
Mar 29, 2010
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Scientists in Michigan and California are reporting an advance toward development of a new generation of drugs that treat disease by orchestrating how genes in the body produce proteins involved in arthritis, cancer and a ...
Biochemistry
Jun 4, 2009
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Dr. Esther Chang describes the most recent developments in human trials of the first systemic, non-viral, tumor-targeted, nanoparticle method designed to restore normal gene function to tumor cells while completely bypassing ...
Bio & Medicine
Apr 20, 2009
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A small piece of RNA, or microRNA (miRNA), ratchets down the activity of the tumor-suppressor gene p53, according to a study by Whitehead Institute and National University of Singapore researchers.
Cell & Microbiology
Mar 17, 2009
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Cancer is simultaneously one of the most common and devastating diseases in our society. So working out new ways to treat it is an enduring scientific challenge.
Biochemistry
Mar 17, 2022
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Lysine methylation is one of the most important covalent modifications involved in diverse cellular processes. Methylation of histone H3 Lys4 (H3K4), predominantly associated with actively transcribed genes, is mainly mediated ...
Molecular & Computational biology
Jul 22, 2020
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The gene p53 is extremely important in cell biology and, hence, the world of cell replacement therapy. Its role is to regulate the cell cycle and halt the formation of tumors, leading to its nickname the "tumor suppressor ...
Cell & Microbiology
Jun 1, 2020
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