Steroid binding to metabolic enzyme

The human cytochrome P450 enzymes are responsible for metabolizing a variety of substances—from lipids (fats) and steroid hormones to drugs and toxic chemicals.

SLAC experiment finds key to natural detoxifier's reactivity

Researchers working at the Department of Energy's SLAC National Accelerator Laboratory have discovered that a mere 9-trillionths-of-a-meter reduction in the length of a chemical bond dramatically boosts the reactivity of ...

Novel role of progestin signaling in fish spermatogenesis

Cytochrome P450, family 17, subfamily A, polypeptide 1 (cyp17a1) is a critical enzyme involved in gonadal steroidogenesis, including androgen and estrogen production. Among sex steroids, androgen signaling disruption is known ...

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