Stiff, achy knees? Lab-made cartilage gel outperforms the real thing
Over-the-counter pain relievers, physical therapy, steroid injections—some people have tried it all and are still dealing with knee pain.
Over-the-counter pain relievers, physical therapy, steroid injections—some people have tried it all and are still dealing with knee pain.
Materials Science
Aug 11, 2022
0
1542
Osteoarthritis is a debilitating condition that affects at least 27 million people in the United States, and at least 12 percent of osteoarthritis cases stem from earlier injuries. Over-the-counter painkillers, such as anti-inflammatory ...
Bio & Medicine
Sep 26, 2016
0
596
It's now 20 years since the birth of Dolly the sheep, the first mammal to be cloned. This groundbreaking scientific achievement was accompanied by warnings that Dolly might age prematurely because she had been cloned from ...
Biotechnology
Jul 27, 2016
0
37
(PhysOrg.com) -- Manchester scientists have turned embryonic stem cells into the cells that produce cartilage, which could be used to repair damaged and diseased joints.
Biotechnology
Oct 18, 2010
1
0
Some 25 million people in the United States alone suffer from rheumatoid arthritis or its cousin osteoarthritis, diseases characterized by often debilitating pain in the joints. Now researchers at Brigham and Women's Hospital ...
Biochemistry
Apr 13, 2011
0
0
A new osteoarthritis drug combination trialled by University of Sydney researchers could significantly extend the working life of racing and other performance horses and could potentially benefit humans.
Plants & Animals
Jun 30, 2011
0
0
Veterinary scientists at the University of Liverpool have developed a new tool to support clinicians in treatment programmes for osteoarthritis in dogs.
Plants & Animals
Jun 4, 2013
0
0
(Phys.org)—Scientists at the University of Montreal's Quebec Research Group in Animal Pharmacology have found a way to recognize and treat osteoarthritis in cats – a condition that the owner might not notice and that ...
Plants & Animals
Feb 19, 2013
1
0
Predators may keep prey populations healthy by acting as a selective force against genetic diseases. A new study found that wolves select adult moose based on age and osteoarthritis, a chronic disease that can be influenced ...
Plants & Animals
Apr 20, 2022
1
746
A Kansas State University professor's research improving post-surgery pain treatment and osteoarthritis therapy in dogs may help develop better ways to treat humans for various medical conditions.
Plants & Animals
Sep 25, 2012
0
0
Osteoarthritis (OA, also known as degenerative arthritis, degenerative joint disease), is a group of diseases and mechanical abnormalities entailing degradation of joints, including articular cartilage and the subchondral bone next to it. Clinical symptoms of OA may include joint pain, tenderness, stiffness, inflammation, creaking, and locking of joints. In OA, a variety of potential forces—hereditary, developmental, metabolic, and mechanical—may initiate processes leading to loss of cartilage -- a strong protein matrix that lubricates and cushions the joints. As the body struggles to contain ongoing damage, immune and regrowth processes can accelerate damage. When bone surfaces become less well protected by cartilage, subchondral bone may be exposed and damaged, with regrowth leading to a proliferation of ivory-like, dense, reactive bone in central areas of cartilage loss, a process called eburnation. The patient increasingly experiences pain upon weight bearing, including walking and standing. Due to decreased movement because of the pain, regional muscles may atrophy, and ligaments may become more lax. OA is the most common form of arthritis, and the leading cause of chronic disability in the United States.
"Osteoarthritis" is derived from the Greek word "osteo", meaning "of the bone", "arthro", meaning "joint", and "itis", meaning inflammation, although many sufferers have little or no inflammation. Osteoarthritis is not to be confused with rheumatoid arthritis, an inflammatory joint disease. A common misconception is that OA is due solely to wear and tear, since OA typically is not present in younger people. However, while age is correlated with OA incidence, this correlation merely illustrates that OA is a process that takes time to develop. There is usually an underlying cause for OA, in which case it is described as secondary OA. If no underlying cause can be identified it is described as primary OA. "Degenerative arthritis" is often used as a synonym for OA, but the latter involves both degenerative and regenerative changes.
OA affects nearly 27 million people in the United States, accounting for 25% of visits to primary care physicians, and half of all NSAID (Non-Steroidal Anti-Inflammatory Drugs) prescriptions. It is estimated that 80% of the population will have radiographic evidence of OA by age 65, although only 60% of those will show symptoms. In the United States, hospitalizations for osteoarthritis soared from about 322,000 in 1993 to 735,000 in 2006.
This text uses material from Wikipedia, licensed under CC BY-SA