Deciphering potent DNA toxin's secrets

One of the most potent toxins known acts by welding the two strands of the famous double helix together in a unique fashion which foils the standard repair mechanisms cells use to protect their DNA.

How RNA formed at the origins of life

A single process for how a group of molecules called nucleotides were made on the early Earth, before life began, has been suggested by a UCL-led team of researchers.

Oddball enzyme provides easy path to synthetic biomaterials

Materials scientists have written the recipe on how to use an oddball enzyme to build new biomaterials out of DNA. The work provides instructions for researchers the world over to build self-assembling molecules for applications ...

Cow embryos reveal new type of chromosome chimera

I've often wondered what happens between the time an egg is fertilized and the time the ball of cells that it becomes nestles into the uterine lining. It's a period that we know very little about, a black box of developmental ...

Crystal structure of PKG I suggests a new activation mechanism

Protein kinases, most scientists would agree, regulate nearly every aspect of cell life. It is no surprise, then, that having faulty protein kinases may lead to a number of human conditions, including cardiovascular diseases, ...

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