Cell nuclei harbor factories that transcribe genes

Our genetic heritage is contained—and protected—in the nucleus of the cells that compose us. Copies of the DNA exit the nucleus to be read and translated into proteins in the cell cytoplasm. The transit between the nucleus ...

Dissecting the brain's primary developmental engine

(Phys.org) —Last month, researchers reported the creation of the first primitive brain-like structures made from human stem cells. To create the complex morphology of these cerebral organoids, cells within a proliferating ...

The 'weakest link' in the aging proteome

Proteins are the chief actors in cells, carrying out the duties specified by information encoded in our genes. Most proteins live only two days or less, ensuring that those damaged by inevitable chemical modifications are ...

Copy of the genetic makeup travels in a protein suitcase

Scientists from the Institute for Physical and Theoretical Chemistry at the University of Bonn have succeeded for the first time in the real time filming of the transport of an important information carrier in biological ...

On the move for repair

Scientists from the Friedrich Miescher Institute for Biomedical Research have elucidated mechanisms that control DNA movement in the nucleus. They found that DNA with double-strand breaks moves more than undamaged DNA, thereby ...

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