(PhysOrg.com) -- Computational biochemist Frank Alber compares determining the architecture of a macromolecular machine to solving a jigsaw puzzle.
Biochemistry
Aug 19, 2009
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A team led by Naoko Imamoto of the RIKEN Advanced Science Institute in Wako, Japan, has uncovered processes governing the formation of functionally important structures called nuclear pore complexes (NPCs) in dividing human ...
Cell & Microbiology
Oct 18, 2010
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Researchers at Delft University of Technology and the University of Basel have established a biomimetic nanopore that provides a unique test and measurement platform for the way that proteins move into a cell's nucleus. In ...
Bio & Medicine
Jun 20, 2011
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To understand how cells function, scientists study how their different components—from single molecules to multiple organelles—work together. Using traditional structural biology techniques, they can look at individual ...
Molecular & Computational biology
Dec 21, 2021
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130
Like loading dock managers at a shipping warehouse, nuclear pore complexes act as gatekeepers to the headquarters of the cell, controlling traffic out of the nucleus.
Bio & Medicine
Aug 25, 2023
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17
Nuclear pore complexes are tiny channels where the exchange of substances between the cell nucleus and the cytoplasm takes place. Scientists at the University of Basel report on startling new research that might overturn ...
Cell & Microbiology
Sep 4, 2017
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2
(PhysOrg.com) -- To protect their DNA, cells in higher organisms are very choosy about what they allow in and out of their nuclei, where the genes reside. Guarding access is the job of transport machines called nuclear pore ...
Cell & Microbiology
Aug 18, 2009
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0
A team of ETH researchers led by Karsten Weis has developed a method that allows them to study the assembly process for large protein complexes in detail for the first time. As their case study, the biologists chose one of ...
Cell & Microbiology
Dec 22, 2020
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26
Fluorescent microscopy makes use of molecules, such as green fluorescent protein (GFP), that emit colored light when illuminated with light of a specific wavelength. Molecules like GFP can be used to label proteins of interest ...
Biochemistry
Sep 21, 2010
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0
One of the key reasons for cancer mortality is the highly invasive behaviour of cancer cells, which is often due to aggressive metastasis. Metastasis is facilitated by various growth factors and cytokines secreted from cells ...
Bio & Medicine
Jun 30, 2017
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