DNA strands often 'wiggle' as part of genetic repair

Sometimes, the molecules that make up life exhibit strange behavior. For instance, in simple organisms such as yeast, when genetic material becomes damaged, the affected DNA strands increase their motion, waving about inside ...

Nuclear pore complex successfully mapped and diagramed

(Phys.org)—Two teams of researchers taking different approaches have successfully mapped and diagramed the nuclear pore complex (NPC)—protein complexes that make up the pores in the nuclear envelope that allow or prevent ...

Hubble sees a celestial swan and butterfly

(Phys.org) -- This image from the Hubble Space Telescope shows planetary nebula NGC 7026. Located just beyond the tip of the tail of the constellation of Cygnus (The Swan), this butterfly-shaped cloud of glowing gas and dust ...

Chromosome 'anchors' organize DNA during cell division

For humans to grow and to replace and heal damaged tissues, the body's cells must continually reproduce, a process known as "cell division," by which one cell becomes two, two become four, and so on. A key question of biomedical ...

Nuclear pore complex outer rings: No longer 'one size fits all'

In eukaryotic cells, the nucleus is walled off from the rest of the cell by the nuclear envelope. All transport into and out of the nucleus occurs via cylindrical channels called nuclear pore complexes (NPCs) that penetrate ...

The role of H3K9 in bringing order to the nucleus

(Phys.org)—Scientists from the Friedrich Miescher Institute for Biomedical Research have elucidated the histone modifications that lead to the sequestration of silent genes at the nuclear periphery. In a study published ...

Pore 'vision' improved

A team led by Naoko Imamoto of the RIKEN Advanced Science Institute in Wako, Japan, has uncovered processes governing the formation of functionally important structures called nuclear pore complexes (NPCs) in dividing human ...

How cells handle broken chromosomes

(PhysOrg.com) -- After being recognized and initially processed by the cellular machinery, the broken chromosome is extensively scanned for homology and the break itself is later tethered to the nuclear envelope. Thus the ...

Programming cells: The importance of the envelope

In a project that began with the retinal cells of nocturnal animals and has led to fundamental insights into the organization of genomic DNA, researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich show how the nuclear ...

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