Chromosome 'anchors' organize DNA during cell division

For humans to grow and to replace and heal damaged tissues, the body's cells must continually reproduce, a process known as "cell division," by which one cell becomes two, two become four, and so on. A key question of biomedical ...

The role of H3K9 in bringing order to the nucleus

(Phys.org)—Scientists from the Friedrich Miescher Institute for Biomedical Research have elucidated the histone modifications that lead to the sequestration of silent genes at the nuclear periphery. In a study published ...

Hubble sees a celestial swan and butterfly

(Phys.org) -- This image from the Hubble Space Telescope shows planetary nebula NGC 7026. Located just beyond the tip of the tail of the constellation of Cygnus (The Swan), this butterfly-shaped cloud of glowing gas and dust ...

DNA 'off switch' may reverse premature aging

The secret to preventing or reversing premature aging may be found in a DNA “off switch” that humans share with common yeast, according to new research from the University of Toronto.

Pore 'vision' improved

A team led by Naoko Imamoto of the RIKEN Advanced Science Institute in Wako, Japan, has uncovered processes governing the formation of functionally important structures called nuclear pore complexes (NPCs) in dividing human ...

Chromosomes dance and pair up on the nuclear membrane (w/ Video)

(PhysOrg.com) -- Meiosis - the pairing and recombination of chromosomes, followed by segregation of half to each egg or sperm cell - is a major crossroads in all organisms reproducing sexually. Yet, how the cell precisely ...

How cells handle broken chromosomes

(PhysOrg.com) -- After being recognized and initially processed by the cellular machinery, the broken chromosome is extensively scanned for homology and the break itself is later tethered to the nuclear envelope. Thus the ...

Lamin B locks up Oct-1

A large fraction of the transcription factor Oct-1 is associated with the inner nuclear envelope, but how and why it is retained there was unknown.

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