New research aims to unlock painkilling secrets of deadly snail venom
The deadly venom of a poisonous sea snail could hold the key to developing new medicines including more effective, less addictive forms of pain relief.
The deadly venom of a poisonous sea snail could hold the key to developing new medicines including more effective, less addictive forms of pain relief.
Biochemistry
Mar 30, 2022
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10
Some studies have shown that nicotine, an addictive substance in electronic cigarettes, increases the risk of cardiovascular and respiratory disorders. But to get a full understanding of its potential health effects, a real-time ...
Analytical Chemistry
Dec 08, 2021
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5
Recently, a research group led by Chu Yannan and Huang Chaoqun from the Institute of Health & Medical Technology of the Hefei Institutes of Physical Science (HFIPS) developed an effective method for on-site detection of methamphetamine ...
Biochemistry
Jun 07, 2021
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7
UT Southwestern researchers have identified the structure of a key member of a family of proteins called nicotinic acetylcholine receptors in three different shapes. The work, published online today in Cell, could eventually ...
Molecular & Computational biology
Mar 17, 2021
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61
Second- and thirdhand tobacco smoke have received lots of attention, but much less is known about the compounds deposited on surfaces from cannabis smoke. Now, researchers reporting in ACS' Environmental Science & Technology ...
Other
Dec 02, 2020
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72
Researchers at UT Southwestern Medical Center have uncovered the detailed shape of a key protein involved in muscle contraction. The report, published today in Neuron, may lead to improved understanding of muscle-weakening ...
Molecular & Computational biology
Apr 15, 2020
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294
As smokers know all too well, nicotine is highly addictive. It's hard to quit smoking, a habit that claims the lives of more than seven million people each year.
Biochemistry
Jan 13, 2020
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43
UT Southwestern researchers today published in Nature atomic-scale blueprints of the most abundant class of brain nicotinic acetylcholine receptors. A structural understanding of the protein, found in neurons, could lead ...
Biochemistry
May 02, 2018
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24
Many people who smoke or chew tobacco can't seem to escape nicotine's addictive properties. Studies show that women in particular seem to have a harder time quitting, even with assistance, when compared to men. Now, scientists ...
Other
Nov 01, 2017
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2
Nicotine-laced nectar can speed up a bumblebee's ability to learn flower colours, according to scientists at Queen Mary University of London (QMUL).
Plants & Animals
May 16, 2017
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261
Nicotine is an alkaloid found in the nightshade family of plants (Solanaceae) which constitutes approximately 0.6–3.0% of dry weight of tobacco, with biosynthesis taking place in the roots, and accumulating in the leaves. It functions as an antiherbivore chemical with particular specificity to insects; therefore nicotine was widely used as an insecticide in the past, and currently nicotine analogs such as imidacloprid continue to be widely used.
In low concentrations (an average cigarette yields about 1 mg of absorbed nicotine), the substance acts as a stimulant in mammals and is one of the main factors responsible for the dependence-forming properties of tobacco smoking. According to the American Heart Association, "Nicotine addiction has historically been one of the hardest addictions to break." The pharmacological and behavioral characteristics that determine tobacco addiction are similar to those that determine addiction to drugs such as heroin and cocaine. Nicotine content in cigarettes has actually slowly increased over the years, and one study found that there was an average increase of 1.6% per year between the years of 1998 and 2005. This was found for all major market categories of cigarettes.
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