Becoming a nerve cell: Timing is of the essence

Mitochondria are small organelles that provide the energy critical for each cell in our body, in particular, in the energy-demanding brain. In this week's edition of Science, a Belgian team of researchers led by Pierre Vanderhaeghen ...

Lipid metabolism controls brain development

Neural stem cells are not only responsible for early brain development—they remain active for an entire lifetime. They divide and continually generate new nerve cells and enable the brain to constantly adapt to new demands. ...

Understanding congenital heart defects, one chicken at a time

Approximately 10 percent of infants are born with a congenital heart defect, with one of the most common being persistent truncus arteriosus—a hole in the heart. In a healthy baby, deoxygenated blood is pumped through a ...

Embryo's early development revealed in a dish

During embryonic development, the entire nervous system, the skin and the sensory organs emerge from a single sheet of cells known as the ectoderm. While there have been extensive studies of how this sheet forms all these ...

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