Scientists at EPFL have developed PeSTo, an AI model that can predict, with high confidence, the binding interfaces of proteins when they bind other proteins, nucleic acids, lipids, ions, and small molecules. The model's ...
Biotechnology
May 10, 2023
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191
Professor Nicolas Doucet and his team at Institut national de la recherche scientifique (INRS) made a major breakthrough earlier this year in the field of evolutionary conservation of molecular dynamics in enzymes. Their ...
Evolution
May 8, 2023
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131
Everyone can use a little stress relief, even bacteria. Now, researchers from Japan have found that a bacterial nanomachine with an unusual cellular location can protect cells from stressful environments.
Cell & Microbiology
Apr 14, 2023
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4
Proteins are components of every cell. How they have changed in the course of evolution for the purpose of taking on new functions in the body, has long been a subject of research. The fact that proteins can emerge practically ...
Evolution
Apr 12, 2023
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58
A new biosensor engineered by Penn State researchers offers scientists the first dynamic glimpses of manganese, an elusive metal ion that is essential for life.
Biotechnology
Mar 9, 2023
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51
EPFL researchers have developed a new technique that uses a protein language model for generating protein sequences with comparable properties to natural sequences. The method outperforms traditional models and offers promising ...
Biotechnology
Mar 9, 2023
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9
A team from the Australian National University (ANU) has modified the protein folding properties of bacteria by adding multiple components from the chloroplast of plants. The accomplishment enables the researchers to look ...
Biotechnology
Feb 22, 2023
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71
By studying how enzymes move from one membrane compartment to another inside a cell, scientists at the University of Illinois Chicago have figured out a way to better target cellular proteins, which play a role in many diseases.
Biochemistry
Feb 15, 2023
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90
Scientists have created an AI system capable of generating artificial enzymes from scratch. In laboratory tests, some of these enzymes worked as well as those found in nature, even when their artificially generated amino ...
Biotechnology
Jan 26, 2023
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242
Natural products (NPs) are low-molecular-weight compounds derived from secondary metabolic pathways, which are regulated by hierarchical regulatory networks from cluster-specific regulators to global transcriptional complexes.
Cell & Microbiology
Nov 17, 2022
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3
