Nanopore reveals shape-shifting enzyme linked to catalysis

University of Groningen scientists have observed the characteristics of a single enzyme inside a nanopore. They learned that the enzyme can exist in four different folded states, or conformers, that play an active role in ...

Scientists sequence the genome of basmati rice

Using an innovative genome sequencing technology, researchers assembled the complete genetic blueprint of two basmati rice varieties, including one that is drought-tolerant and resistant to bacterial disease. The findings, ...

Nanopore sequencing of African swine fever virus

African swine fever (ASF) is one of the most pathogenic viral diseases in pigs caused by African swine fever virus (ASFV). The fatality rate is almost 100%, which brings huge economic losses to the hog industry in countries ...

A tool to democratize nanopore research

A nanopore is a tiny hole in a thin membrane with a diameter of around a billionth of a meter, or about the width of a single DNA molecule. The potential applications of these nanopores are so diverse—from medicine to information ...

Researchers create synthetic nanopores made from DNA

In 2015, the first commercial nanopore DNA sequencing device was introduced by Oxford Nanopore Technologies. Based on a synthetically engineered transmembrane protein, nanopore sequencing allows long DNA strands to be channelled ...

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