Starving tuberculosis of sugars may be a new way to fight it

Tuberculosis is a devastating disease that claims over 1.5 million lives each year. The increase in TB cases that are resistant to the current antibiotics means that novel drugs to kill Mycobacterium tuberculosis (Mtb) are ...

Study could explain tuberculosis bacteria paradox

Tuberculosis bacteria have evolved to remember stressful encounters and react quickly to future stress, according to a study by computational bioengineers at Rice University and infectious disease experts at Rutgers New Jersey ...

How the TB bacterium develops rapid resistance to antibiotics

For a slow-growing microbe that multiplies infrequently, Mycobacterium tuberculosis, the pathogen that causes tuberculosis (TB) has long puzzled researchers as to how it develops resistance to antibiotics so quickly, in a ...

Antibacterial prodrug by targeting intracellular metabolite

National University of Singapore researchers have developed an approach to selectively target pathogenic bacteria by harnessing an intracellular metabolite known as formate, abundant in these bacteria, as a new antimicrobial ...

Blocking iron transport could stop tuberculosis

One of the most devastating pathogens that lives inside human cells is Mycobacterium tuberculosis, the bacillus that causes tuberculosis. According to the World Health Organization, 1.5 million people died in 2019 from this ...

Antacid helps tuberculosis bacteria to survive

In 2017, some 10 million people suffered from tuberculosis and 1.6 million died of the disease. One reason that infection with Mycobacterium tuberculosis is so difficult to treat is because the bacteria can hide inside immune ...

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