Eliminating damaged germline cells preserves germline integrity

The germline is the cell lineage of an organism that passes on its genetic material to its progeny. Genetic damage to the germline can cause developmental defects and even death of that same progeny. It is thought that biological ...

Matchmaking with consequences

Most human tumours have one thing in common: They harbour drastically increased amounts of the so-called Myc proteins. Animal experiments show that such high Myc concentrations contribute to causing cancer. But Myc proteins ...

A 'social control' system guarantees embryonic stem cell purity

A sophisticated system of "social control" operating between neighboring cells allows embryos to protect the purity of their pluripotent cell population, which is able to generate all body tissues. This system works through ...

A surplus with consequences

Why do healthy cells become malignant and proliferate uncontrollably? Scientists of the University of Würzburg have investigated the role of a special protein in this process and settled and old controversy.

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